GLP-1 medications have reshaped what a weight loss center in Houston actually offers, and the clinics here have logged nearly 2,500 Google reviews between them. Ratings run from 4.7 to 4.8 across the group, tight enough that the real differences show up in how each clinic structures its program and pricing rather than in the star count alone.
Short answer: Clinic 45 leads by far on volume with 1,368 reviews at 4.8 stars, offering weight loss injections alongside aesthetic and internal medicine services. Houston Weight Loss Center - Katy (4.8, 264 reviews) and Texas Weight Loss - Houston Southwest (4.7, 395 reviews) round out the group, with physician-supervised programs starting with a consultation before any medication is prescribed.
#1 Overall🕑 Open 6 days/wk↩ Responds to reviews
Clinic 45
4.8★★★★★1,368 Google reviews
Clinic 45, owned and supervised by Dr. Joseph E. Sleiman, is an independent weight loss and aesthetic center with 20 years of history and six locations across Texas, including its Gulf Freeway office in Houston. The clinic pairs weight loss injections and supplements with aesthetic services like Botox and dermal fillers, plus internal medicine consultations. It's by far the most-reviewed weight loss center on this list.
What people praise
- Reviewers describe real weight loss results and improved diabetes management under physician supervision
- Long operating history with 20 years in business
- Multiple service lines available in one visit, including aesthetics and internal medicine
- Consistent positive feedback about specific providers by name
Worth knowing
- Several reviewers describe front-desk staff as unwelcoming or curt on the phone
- One reviewer flagged side effects when switching to a compounded medication, and cautioned others to watch for changes
Reputation scorecardrank in Houston
Review volume1,368 · 96th
Info completenesssite · phone · hours
Rating breakdown90% 5-star
✓ VerifiedSource: Google
Our take: The most-reviewed clinic in Houston by a wide margin, and a reasonable default for anyone wanting weight loss care bundled with broader wellness services under one roof.
📍8221 Gulf Fwy #400, Houston, TX 77017
#2🕑 Open 5 days/wk↩ Responds to reviews
Texas Weight Loss - Houston Southwest
4.7★★★★★395 Google reviews
Texas Weight Loss - Houston Southwest is part of a six-location chain across Texas offering a structured, physician-guided weight loss program built around GLP-1 support, low-carb diet guidance, and monthly follow-up visits. The Southwest Freeway location handles the Houston side of the practice, with telemedicine options also available. The program is designed as a three-step process starting with a consultation.
What people praise
- Structured, repeatable program with clear monthly check-ins
- Reviewers who stuck with the program describe strong, lasting results
- Telemedicine option available for those who prefer not to visit in person
- 20 years of combined operating history across its Texas locations
Worth knowing
- Multiple reviewers describe long wait times and unhelpful communication with front-desk staff
- A no-show fee dispute was raised by at least one longtime patient
Reputation scorecardrank in Houston
Info completenesssite · phone · hours
Rating breakdown86% 5-star
✓ VerifiedSource: Google
Our take: A solid structured option for GLP-1-based programs, though it's worth confirming the no-show and cancellation policy up front given the complaints in its reviews.
📍11226 Southwest Fwy Ste B, Houston, TX 77031
#3🕑 Open 5 days/wk↩ Responds to reviews
Houston Weight Loss Center - Katy
4.8★★★★★264 Google reviews
Houston Weight Loss Center's Katy location is part of a practice operating since 1996 across three Houston-area sites, offering physician and nurse-practitioner supervised weight management, including GLP-1 medications like semaglutide and tirzepatide, alongside peptide therapy. Every plan starts with a clinical evaluation before a provider designs a personalized approach. The Katy office holds the highest rating among the larger practices on this list.
What people praise
- Reviewers consistently describe fast, low-wait visits
- Praised for detailed monthly progress reports
- Physician and nurse-practitioner led, treating weight as a medical condition
- Reviewers highlight reasonable to great pricing for the program
Reputation scorecardrank in Houston
Info completenesssite · phone · hours
Rating breakdown92% 5-star
✓ VerifiedSource: Google
Our take: A strong pick for anyone who wants a long-established, physician-led program with minimal wait times and clear monthly tracking.
📍23217 Red River Dr, Katy, TX 77494
#4🕑 Open 6 days/wk
Woodforest Weight Loss
4.7★★★★★248 Google reviews
Woodforest Weight Loss, part of Woodforest Pediatric & Family Clinic in east Houston, offers weight loss packages combining phentermine or HCG with B-12 or lipotropic injections, bloodwork, and physician consultations. Its published packages start at $79 for a basic phentermine plan and scale up to $289 for combined HCG and phentermine plans with multiple injections. The clinic also runs family and pediatric practice services alongside its weight loss line.
What people praise
- Published package pricing starting at $79, unusually transparent for this category
- Reviewers praise quick, knowledgeable service at check-in and for injections
- Pharmacy located in the same parking lot for convenience
- Reviewers report visible weight loss progress from the program
Worth knowing
- Multiple reviewers describe a full voicemail box and difficulty reaching the office by phone
- At least one reviewer was turned away after a walk-in cutoff time despite driving some distance
Reputation scorecardrank in Houston
Info completenesssite · phone · hours
Rating breakdown92% 5-star
✓ VerifiedSource: Google
Our take: The most budget-transparent option on this list thanks to its published package pricing, though call ahead rather than relying on the phone line given the reviews about reaching the office.
📍13018 Woodforest Blvd Ste B & C, Houston, TX 77015
#5🕑 Open 5 days/wk↩ Responds to reviews
Champion Health and Wellness Clinics
4.7★★★★★217 Google reviews
Champion Health and Wellness Clinics, located on San Felipe Street, offers weight loss alongside hormone pellet therapy (Biote) and other wellness services under Dr. Cynthia Lynn Champion. The clinic handles GLP-1 prescriptions like phentermine and semaglutide alongside its hormone therapy line. Reviewers describe a mix of straightforward medication-focused visits and longer wellness consultations.
What people praise
- Reviewers praise fast intake and delivery for GLP-1 prescriptions
- Described as responsive and professional in communication
- Some reviewers highlight in-depth, educational consultations about their broader health
- Multiple service lines available for those combining hormone and weight-loss care
Worth knowing
- One detailed reviewer felt a hormone therapy consultation shifted into a supplement sales conversation, which the practice disputed point by point in its response
Reputation scorecardrank in Houston
Info completenesssite · phone · hours
Rating breakdown91% 5-star
✓ VerifiedSource: Google
Our take: A reasonable choice for anyone specifically interested in combining hormone therapy with weight-loss medication, though ask up front exactly what a consultation will and won't include.
📍4295 San Felipe St #235, Houston, TX 77027
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Health information disclaimer: This directory is informational only and not medical advice. Rankings reflect publicly available Google ratings and review volume, not clinical outcomes. Verify any practitioner’s credentials and registration with the relevant medical board before booking.
How we score
Every number on this page is computed from public Google data on the date shown, not from opinion or payment. Rating is the clinic’s live Google star average. Review volume is how many patients have rated them, ranked against other Houston weight loss centers. Confidence weighs the rating by that volume, so a 4.8 from over a thousand reviews carries more weight than a 4.8 from a few hundred. Recency reflects how recently patients are still leaving reviews. No business can pay to change these numbers.
How much does a weight loss program cost in Houston? (2026)
Weight loss center pricing in Houston depends heavily on the type of program: GLP-1 medications like semaglutide and tirzepatide typically cost more than phentermine-based plans, and packages vary by how many injections, labs, and consultations are included. One clinic on this list publishes package pricing starting at $79 for a basic phentermine plan and scaling to around $289 for combined medication and injection packages; GLP-1 medication programs elsewhere on this list are typically priced separately and not published online, so ask for the full monthly cost, including medication, before enrolling.
| Job | Typical price |
|---|
| Basic phentermine package (30 days, 1 injection, bloodwork, consult) | $79 |
| Combined HCG + phentermine package (60 days, multiple injections, bloodwork, consult) | $289 |
Figures shown are published 2026 package pricing from Woodforest Weight Loss’s own website, cited directly rather than a third-party estimate. Other clinics on this list do not publish fixed pricing; always confirm the full monthly cost, including medication, before enrolling in a GLP-1 or hormone therapy program.
Serving all of Houston
The weight loss centers above cover Houston and the surrounding metro, including Gulf Freeway, Southwest Houston, Katy, Woodforest, and the San Felipe corridor. Searching for a weight loss center near me? Every listing below shows a live phone number and directions so you can find the closest office.
What to ask before you choose a weight loss center
- Is the program physician or nurse-practitioner supervised?
- What’s the full monthly cost, including medication, labs, and follow-up visits?
- Is the medication brand-name or compounded, and how does that affect cost or availability?
- What happens if I miss an appointment or need to cancel?
- Do you offer telemedicine visits if I can’t make it in person?
Frequently asked questions
How did you choose these weight loss centers?
We started from weight loss centers in Houston with a public Google presence, then ranked by rating, review volume, consistency, and recency. See How we score above.
Are these rankings paid?
No. Rankings come from the public Google data in the scorecard. A business can pay to be a Featured Partner, which adds a badge and top placement, but that never changes another business’s score or position on the underlying data.
How often is this updated?
The data carries a verified date (August 2026 on this page). We refresh listings periodically so ratings and review counts stay current.
Do these Houston weight loss centers offer GLP-1 medications?
Several clinics on this list, including Texas Weight Loss and Houston Weight Loss Center, specifically list GLP-1 medications like semaglutide and tirzepatide. Ask directly about medication type, sourcing, and monthly cost before enrolling.
Is a consultation required before starting a weight loss program in Houston?
Yes, every clinic on this list requires an initial consultation and, in most cases, bloodwork before a provider prescribes medication or builds a program. This is a safety step, not just paperwork, and lets the provider check whether a given medication is appropriate for you.
The bottom line
Clinic 45 is the safe default given its size and range of services, while Houston Weight Loss Center - Katy stands out for its long history and fast, well-documented visits. Whichever you choose, get the full monthly cost in writing, including medication, before you enroll.
